According to ESRB, this game contains: Violence
Parents should be mostly fine with the game, as the game's violence is cartoonishly inoffensive. Still, it is a game where giant monsters devour innocent bystanders while destroying buildings—content that may prove a little too intense for very young children.
Fans of the Rampage series, be warned—the original Rampage and Rampage: World Tour are included on the disc, so prepare to have your fond memories dispelled.
Deaf and Hard of Hearing gamers will be absolutely fine. There isn't any plot to subtitle, and missing what few audio cues there are won't affect your gameplay too badly.