According to ESRB, this game contains: Fantasy Violence, Partial Nudity
Parents don't have a lot to worry about, although they should be aware that a very small number of the cards do feature sexually suggestive artwork. It's never extremely explicit, though. The game will probably be vastly too difficult for young ones anyway, so it might be a moot point. There is no questionable language, and no blood or gore.
Fans of CCGs or Monopoly, this is your game. Buy it now. I would also strongly recommend Monster Rancher Battle Cards on the PlayStation. It doesn't have the board game element, but the cards aspect is extremely well done and involves much strategy and planning. Great stuff if you're the type.
Multiplayer maniacs can have up to four people at once without the need of a multitap. Team or competitive play is available with a multitude of settings, and trading cards is also possible.
Deaf and Hard of Hearing gamers will have no problems playing the game. All dialogue comes with text, and there are no significant auditory cues BUT the ending CG is voice-only, with no text. It's not enough for me to recommend against the game, but I'd imagine it's a serious bummer to get through 16 arduous stages and not be able to enjoy the ending.