According to ESRB, this game contains: Cartoon Violence
Parents really don't have that much to worry about in terms of content. Power of JuJu was partly designed by Nickelodeon, and it isn't any worse than SpongeBob or the Rugrats. The only thing that might be a problem the occult-ish elements in this game like the mummies, and tribal mysticism. And I can only think this might be a problem for only the most religious of parents. The poor layout might pose a bigger problem for young ones.
Fans of Nickelodeon cartoons might enjoy, but are more likely to be disappointed. The game doesn't get as strange or bizarre as the other Nickelodeon shows, and feels watered down in many ways.
Deaf and Hard of Hearing gamers was partly designed by Nickelodeon, and it isn't any worse than might want to note that there is quite a lot of dialogue in this game, but not enough subtitles to go with it.