According to ESRB, this game contains: Language, Violence
Parents don't have much to worry about. The violence is basically punching nondescript criminals and then wrapping them up in webbing. However, the second playable character (Venom) looks a little nastier than Spider-Man, and he gains energy by sucking people inside his body and then spitting them back out. It's not very graphic, but it is sort of disturbing. I don't recall any instances of questionable language despite the warning on the back of the box, so I feel safe in saying that most kids will be okay with the content here.
Action gamers will find a short, boring exercise in repetition occasionally broken up by some OK boss battles. The graphics look great and the cutscenes are amazing, but the coolness of the visuals wears off in a hurry when compared to the absolute dullness of the gameplay. I really wanted to like this game, but I just couldn't.
Spider-Man fans might want to check this game out based on the fact that it is created from the comic book and not the movie. Personally, I am not familiar with this particular series, and its reworking of the classic mythos. However, you probably have to be a serious fan to actually like this game—my advice is to hold off until it hits bargain bins.
Deaf and Hard of Hearing gamers are totally screwed. There are no subtitles or text anywhere in the game, meaning that the story and cutscenes are completely inaccessible. This kind of thing is inexcusable in this day and age, and I'm very disappointed to report it. The game is so weak that completely missing out on the story parts means that there's absolutely nothing here to enjoy. Boo, Treyarch!